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Our Technology

We combine high performing spectroscopy hardware, proprietary spectra processing methods, and user-friendly software.

The case for the Amplifi ID Drug Analysis System being opened, revealing the drug analyzer
A Bulk Scan being performed on a white powder in a baggy, using the Amplifi ID Drug Analysis System
Someone holding part of the Amplifi ID Trace Scan Test Kit
Inserting a Trace Scan cartridge into the Amplifi ID drug analyzer

How it Works: Enhanced Molecular Fingerprinting

Amplifi ID leverages the power of Raman spectroscopy and surface enhanced Raman scattering (SERS) to detect unique scattered light signatures from samples. Raman signatures are so information rich and specific to organic substances that scientists have coined them “molecular fingerprints”. Even more, the Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG) defines Raman as a Category A technique, as it can "provide the highest level of selectivity through structural information".

A graphic illustrating the idea of "chemical fingerprinting", which shows a Fentanyl Raman spectra
Screenshot of the Amplifi ID web app that shows that Fentanyl was detected using Trace Scan. The substance's Raman spectra is compared to a raw Fentanyl spectra for certainty

The complex structural information is analyzed by our expert-designed signal processing methods and database of molecular fingerprints. When fingerprint matches are made, Amplifi ID will communicate to you what has been identified  in plain language.


The identification algorithms are designed to be explainable, and you can use our visualization tools to toggle between known references of the chemical in question to understand the spectral evidence behind a result.

The Value of Detailed Chemical Fingerprinting

The high level of detail that Raman signatures provide help to give operators a more nuanced and specific understanding of what is in their sample. We can see an example of why this is important by looking at a Drug Checking use case.

 

Here you can see the chemical structures and Raman signatures for two separate substances. While mostly similar, there are minor yet distinct differences in their profile. 

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These subtle differences are key to differentiating between standard Cocaine Hydrochloride and Cocaine Base (Freebase or Crack).

Structural formula and Raman spectra of Cocaine
Structural formula and Raman spectra of Cocaine (base)

Want to learn more?

An introduction to the science behind Raman and FTIR spectroscopy, and the strengths and weaknesses of each method for drug identification.

Check out our 2024 white paper for this non-opiate sedative, where we demonstrate Amplifi ID's ability to detect it in street drugs, and compare our performance to FTIR.

For any questions you may have, technical or otherwise, please reach out via our contact form and we will do our best to get back to you within two business days.

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